On-Demand Presentation

Multi-Angle Light Scattering:
Applicability of MALS Detection in Understanding Novel Macromolecules and their Structure-Property Relations

On-Demand
Explore the main uses of MALS including molecular weight determination, aggregation screening, molecular size, and shape.

By viewing this presentation, you will:

  • Review the fundamentals of light scattering
  • Learn what information MALS can provide about your material

Event Overview

Multi-angle light scattering (MALS), a technique that calculates molecular weight and size through the measurement of light scattered across many angles, is a powerful tool that has become ubiquitous in recent years. What was once a niche detector in the polymer world has rapidly become a useful detector in many emerging fields of interest.

In this presentation, we will investigate the main uses of MALS including molecular weight determination, aggregation screening, molecular size, and shape. We will further relate these structure-property relationships back to bulk material behaviour and CQAs within the materials and pharma/biopharma spaces. We will also show the new 1260 MALS detector from Agilent and examine some use cases that we have seen with some of our academic and industrial collaborators to showcase the wide variety of MALS applications and configurations and highlight the benefits such a detector can add to macromolecular research.

What you need to know:

Format: On-demand

Duration:  54 minutes

Presenters

Steve Rosa
GPC/SEC Product Specialist, Agilent Technologies

Steve received a BS from UMass Amherst in 2016. After graduating, he worked in the Polymer Science and Engineering department at UMass with a focus on the synthesis of zwitterionic small molecules for use in interlayers as well as halogen-free flame-retardant polymers. Steve joined PSS in 2019 as a Technical Support & Application Specialist and has been in his current role at Agilent as a GPC/SEC Product Specialist since 2022. Steve currently supports the whole Agilent GPC/SEC portfolio covering everything from instrumentation to software.

Lorena Lopez
Application Scientist, Agilent Technologies

Lorena Lopez is an LC Application Scientist with Agilent Technologies and is currently based out of the Agilent facilities in Lexington, Massachusetts. She has been with Agilent for almost 10 years, tightly involved within liquid chromatography, capillary electrophoresis, and dissolution instrumentation. She also spent several years in life sciences research developing both analytical LC and biopharma workflows, areas where she has been focusing for the last couple of years within her current role.

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