Tutorials

How to Reduce LC Method Development Time

Discover how the Pro EZLC Chromatogram Modeler can simplify and speed up your liquid chromatography method development.

Learn from the experts...

The Pro EZLC Chromatogram Modeler is the latest addition to Restek’s suite of virtual chromatography software designed to simplify and speed up method development. In this three-part series, Paul Connolly introduces the tool and then goes through two specific use cases: PFAS as well as psychoactive. Learn how the Pro EZLC Chromatogram Modeler can make column selection and optimization for LC-MS/MS methods for therapeutic and abuse drugs, nitrosamines, and PFAS compounds easier and faster. Method developers and analysts will appreciate access to a virtual selection of columns to aid in choosing and optimizing methods. They even cover adding novel psychoactive substances to an existing method without the need for an instrument.

  • Learn about the Pro EZLC Chromatogram Modelling tool and how to access it.
  • Learn how to perform LC-MS/MS method development and optimization easier, faster, and without an instrument.

Tutorial 1: LC-MS/MS Method Development and Optimization

The first module covers how the Pro EZLC Chromatogram Modeler can make column selection and optimization for LC-MS/MS methods for therapeutic and abuse drugs, nitrosamines, and PFAS compounds easier and faster. Method developers and analysts will appreciate access to a virtual selection of columns to aid in choosing and optimizing methods.

Tutorial 2: LC-MS/MS Method Development and Optimization of PFAS

This second module explores how the Pro EZLC Chromatogram Modeler can make column selection and optimization for LC-MS/MS methods for PFAS compounds easier and faster. This includes the use of PFAS delay columns and other specializations unique to PFAS analysis. Method developers and analysts will appreciate access to a virtual selection of columns to aid in choosing and optimizing methods.

Tutorial 3: LC-MS/MS Method Development and Optimization of Novel Psychoactive Substances

The third module focuses on how the Pro EZLC Chromatogram Modeler can make column selection and optimization for LC-MS/MS methods for therapeutic and abuse drugs and nitrosamines easier and faster. Method developers and analysts will appreciate access to a virtual selection of columns to aid in choosing and optimizing methods. They even cover adding novel psychoactive substances to an existing method without the need for an instrument.

Presenter:

These tutorials are brought to you in collaboration with Restek and presented by Paul Connolly, Senior Product Manager, Restek Corporation. Paul brought 24 years of analytical and chromatography expertise to Restek, including 16 years performing LC-MS/MS. He earned his BS in biology and a minor in chemistry from the University of Pittsburgh, after which he was an environmental GC, GC-MS, and HPLC chemist for nearly a decade. Paul has also worked as a scientist and was principal investigator, group leader, technical leader, and method developer for a contract research organization providing LC-MS/MS support to the food safety, environmental, animal health, and crop protection industries. Paul was also a bioanalytical laboratory director, providing analytical laboratory services for drug development. As Restek's liquid chromatography product manager, Paul's main focus is to grow and develop the company's LC product lines and to provide customers with high-performing solutions to their LC challenges.

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