This eBook contains a selection of application notes relevant for pharmaceutical and biopharmaceutical analysis using HPLC / (U)HPLC or LC-MS/MS.
Discover an effective method for drug quantitation in biological fluids, a high-throughput analysis for simple fractionation, the application of a dual injection system for the analysis of pharmaceuticals, together with methods for impurity analysis and comprehensive fractionation.
Applications include:
- Ultra-Fast LC-MS/MS Analysis of Drugs in Biological Fluids
- High Efficiency in Workflow from Preparative HPLC to Analytical HPLC
- Application of a Dual Injection (U)HPLC for the Analysis of Pharmaceuticals
- Impurity Analysis in Pharmaceutical Products Using Diode Array Detection
- Comprehensive Fractionation of Herbal Medicine Components by PDA-ELSD Triggered Preparative LC
Learning Outcomes for each Application Note
Ultra-Fast LC-MS/MS Analysis of Drugs in Biological Fluids
- Ultrafast autosampler reduces overall analysis times for higher throughput
- Carryover is kept to an absolute minimum with active rinsing
High Efficiency in Workflow from Preparative HPLC to Analytical HPLC
- Liquid handler is equipped with parallel preparative and analytical flow paths, enabling seamless re-analysis of the collected fractions
- Automated processes increase efficiency for the entire workflow, from fractionation to re-analysis
Application of a Dual Injection (U)HPLC for the Analysis of Pharmaceuticals
- Dual injection technique allows two analyses to be run simultaneously, doubling throughput
- Shows the successful method transfer to superficially porous (SPP) columns
Impurity Analysis in Pharmaceutical Products Using Diode Array Detection
- PDA detector eliminates the effects of stray light during detection
- Delivers outstanding performance over a wide range of concentrations
Comprehensive fractionation can be performed without missing non-UV absorbing compounds
- Graphical user interface provides easy and labor-saving operation for fractionation settings
- Smooth transfer from preliminary analytical LC to preparative purification LC is possible
