By watching this presentation, you will:
- Understand the fundamentals of ion-pair reversed-phase LC/MS for oligonucleotides
- Discover how a single quadrupole detector is used for impurity profiling of anti-sense oligonucleotides
- Learn how fit-for-purpose software for LC/MS analysis in QC lot release can save time and enhance quality
Event Overview
In this webinar, we’ll address analytical challenges faced in late-stage development of therapeutic synthetic oligonucleotides. We’ll highlight the necessity of using advanced methods like liquid chromatography-mass spectrometry (LC/MS) to meet stringent regulatory requirements.
We’ll introduce the Oligo Analysis Accelerator for OpenLab CDS designed to streamline the analytical workflow. This application offers a user-friendly interface and leverages the existing data integrity and compliance architecture of OpenLab CDS, enabling QC scientists to efficiently perform complex methods such as purity, assay, and impurity profiling for therapeutic oligonucleotides.
What you need to know:
Format: On-demand
Duration: Approximately 45 minutes
Who should view it
- Analytical chemists focused on advanced software for large molecule development
- R&D labs developing robust methods for single-stranded oligo therapeutics
- Process scientists optimizing synthesis and purification through in-process control purity results
- QA and QC personnel supporting oligo testing labs
Register and access the bonus content
By registering, you will also have access to the resources below:
Technical Overview: Purity, Assay, and Impurity Profiling of Single-Stranded Oligonucleotides Using Agilent Oligo Analysis Accelerator for OpenLab CDS
This technical overview will address the Oligo Analysis Accelerator (OAA) for Agilent OpenLab CDS. This software add-on acts as the data analysis front end to OpenLab CDS, leveraging built-in technical controls that help meet data integrity and compliance requirements.
Expert FAQ: How Can Software Boost Efficiency in Oligonucleotide QC?
Discover the benefits of digital tools designed specifically for oligonucleotide quality control challenges.
Presenter
Brian Rivera
Software Product Manager, Agilent Technologies
Brian Rivera is a software product manager at Agilent Technologies with 20 years of experience in HPLC analysis of large molecules.
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